Gomaa Mostafa Mohamed <br/><br/>
Effect of multidrug resistance-1 gene polymorphisms on response to cyclosporine in renal transplanted patients /  
 تأثير تنوع جين مقاومة العقاقير على الإستجابة لعقار سيكلوسبورين فى مرضى زرع الكلى 
Gomaa Mostafa Mohamed ; Supervised Magda M. Zaki , Sanaa A. Shafy , Tarek Hussein Elshabony 
 - Cairo :   Gomaa Mostafa Mohamed ,   2012 
 - 219 P. :   charts ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pharmacology 
<br/><br/> The aim of the present work is to study the pharmacogenomics in renal transplanted patients receiving cyclosporine A through assessing the effect of MDR-1 gene polymorphism namely at exon 26 (C3435T) and exon 11 (G1199A) on the pharmacokinetics of the drug. To reach this goal, we studied 40 recent renal transplanted patients receiving cyclosporine (26 males (65%) and 14 females 35% 
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<br/><br/><label>Subjects--Index Terms: </label>Cyclosporine Pharmacogenetic Polymorphism