TY - BOOK AU - Gomaa Mostafa Mohamed AU - Magda Mohamed Zaki , AU - Sanaa Abdelshafy , AU - Tarek Hussein Elshabony , TI - Effect of multidrug resistance-1 gene polymorphisms on response to cyclosporine in renal transplanted patients / PY - 2012/// CY - Cairo : PB - Gomaa Mostafa Mohamed , KW - Cyclosporine KW - Pharmacogenetic KW - Polymorphism N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pharmacology; Issued also as CD N2 - The aim of the present work is to study the pharmacogenomics in renal transplanted patients receiving cyclosporine A through assessing the effect of MDR-1 gene polymorphism namely at exon 26 (C3435T) and exon 11 (G1199A) on the pharmacokinetics of the drug. To reach this goal, we studied 40 recent renal transplanted patients receiving cyclosporine (26 males (65%) and 14 females 35% UR - http://172.23.153.220/th.pdf ER -