Evaluation of viability of BCG vaccine using a conventional viable count method and a tetrazolium salt rapid assay method /
بالطريقة التقليدية و الطريقة السريعة باستخدام ملح التترازوليوم BCG دراسة حيوية لقاح
Ali Mohammed Ali Mohammed ; Supervised Ali Mohamed Kholefy , Hamdallah Hafez Zedan
- Cairo : Ali Mohammed Ali Mohammed , 2012
- 146 P. ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology
The potency of the live attenuated Mycobacterium bovis BCG vaccine is dependent on its content of viable cell. The viability of the organism is essential for the stimulayion of a protective immune response, hence monitoring of the viable count is an integral part of quality control o BCG vaccine. The method, which is recommended by the world health organization (WHO) and European Pharmacopoeia (EP) for control of potency of BCG vaccine, is the conventional viable count