TY - BOOK AU - Rania Elsayed Hussein Abdelrahman AU - Dimitri Mikhailidis , AU - Ibrahim Elibrashy , AU - Mohamed Talaat Abdelaziz , TI - Signaling mechanisms of water soluble curcumin derivative in diabetic cardiovascular complications / PY - 2012/// CY - Cairo : PB - Rania Elsayed Hussein Abdelrahman , KW - Curcumin KW - Diabetes type 1 KW - Diabetic cardiomyopathy N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of - Medical Biochemistry; Issued also as CD N2 - Curcumin has been identified as a potent inducer of heme-oxygenase-1 (HO-1), protein that provides protection against various forms of stress. Diabetic cardiomyopathy characterized by cardiomyocyte hypertrophy, eventually leads to heart failure. Transcriptional co-activator p300 and its interaction with myocyte enhancer factor 2 (MEF2) play a major role in diabetes-induced cardiomyocyte hypertrophy UR - http://172.23.153.220/th.pdf ER -