Shereen Shaker Elhusseny Ahmed <br/><br/>
Prepation of membrane - based systems useful in delivering biologically active materials to skin /  
 تحضير أغشية لاستخدامها كأنظمة لانطلاق المواد الحيوية الى الجلد 
Shereen Shaker Elhusseny Ahmed ; Supervised Aliaa Abdellatif Badawi , Hanan Mohammed Ellaithy , Demiana Ibrahim Nesseem 
 - Cairo :   Shereen Shaker Elhusseny Ahmed ,   2012 
 - 200P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics 
<br/><br/> Thecurrent work has aimed to improve HA therapy in knee OA by developing a novel combined controlled transdermal membrane therapy containing both HA and KT . In this way , easy , painless and continuous HA - KT delivery through the skin into the blood stream could be ensured thus produce stable plasma concentration over a long period and avoiding invasive frequent HA intra - articular injections and KT gastrointestinal complaints associated with all NSAIDs such as bleeding , perforation and peptic ulceration 
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<br/><br/><label>Subjects--Index Terms: </label>Bone mineral density (BMD)  Freund's complete adjuvant (FCA)  Hyaluronic acid (HA)