TY - BOOK AU - Shereen Shaker Elhusseny Ahmed AU - Aliaa Abdellatif Badawi , AU - Demiana Ibrahim Nesseem , AU - Hanan Mohammed Ellaithy , TI - Prepation of membrane - based systems useful in delivering biologically active materials to skin / PY - 2012/// CY - Cairo : PB - Shereen Shaker Elhusseny Ahmed , KW - Bone mineral density (BMD) KW - Freund's complete adjuvant (FCA) KW - Hyaluronic acid (HA) N1 - Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics; Issued also as CD N2 - Thecurrent work has aimed to improve HA therapy in knee OA by developing a novel combined controlled transdermal membrane therapy containing both HA and KT . In this way , easy , painless and continuous HA - KT delivery through the skin into the blood stream could be ensured thus produce stable plasma concentration over a long period and avoiding invasive frequent HA intra - articular injections and KT gastrointestinal complaints associated with all NSAIDs such as bleeding , perforation and peptic ulceration UR - http://172.23.153.220/th.pdf ER -