Sally Tarek Elbanna <br/><br/>
Physical properties and pharmaceutical applications of chitosan nanoparticles loaded with hydrophobic drugs /  
 الخواص الفيزيقية والتطبيقات الصيدلانية لحبيبات نانومترية من الكيتوزان محملة بأدوية كارهة للماء 
Sally Tarek Elbanna ; Supervised Wafaa A. Khalil , Safaa K. H. Khalil 
 - Cairo :   Sally Tarek Elbanna ,   2012 
 - 142P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Biophysics 
<br/><br/> Chitosan nanoparticles were successfully prepared by ionic gelation method . They were loaded with a hydrophobic drug model , warfarin , in order to enhance its bioavailability and controlled release in blood circulation system . To overcome the hydrophobic nature of warfarin , it was complexed with Ý- cyclodextrin . The drug loaded nanoparticles were characterized by SEM , TEM , Zeta potential , FT - IR and UV - visible spectroscopy 
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<br/><br/><label>Subjects--Index Terms: </label>Chitosan nanoparticles  Controlled release  Ionic gelation