TY - BOOK AU - Ibrahim Ahmed Elsaid Mohamed AU - Ahmed Abdelfatah Aboelwafa , AU - Omaima Naeem Elgazayerly , AU - Rawia Mohamed Khalil , TI - A pharmaceutical study on controlled release baclofen tablets / PY - 2012/// CY - Cairo : PB - Ibrahim Ahmed Elsaid Mohamed , KW - Baclofen KW - Gastroretentive KW - Superporous N1 - Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics; Issued also as CD N2 - The main goal of this work is to formulate gastroretentive dosage forms capable of increasing the residence of baclofen at its absorption window and modifying oral baclofen release , in an attempt to counteract the low plasma elimination half - life of baclofen (3 to 4 hours) , minimize dose fluctuation and improve therapeutic response for patients suffering from spasticity and chronic musculoskeletal conditions UR - http://172.23.153.220/th.pdf ER -