Mira Adel Maurice Behnam <br/><br/>
Synthesis and pharmacological evaluation of homomelatonin and 1-benzylmelatonin analogs as ligands for metatonin receptors /  
 تشييد وتقييم فارماكولوجى ل هوموميلاتونين ون 1 بنزايل من مشتقات الميلاتونين كمركبات ماسكة (ليجند) لمستقبلات الميلاتونين 
Mira Adel Maurice Behnam ; Supervised Darius P. Zlotos 
 - Cairo :   Mira Adel Maurice Behnam ,   2011 
 - 175Leaves :   charts , facsimiles ;   30cm 
<br/><br/>Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry 
<br/><br/> The neurohormone melatonin exerts its diverse physiological actions mainly through activation of two G - protein - coupled receptors MT₁ and MT₂ . Extensive SAR - studies have been carried out revealing both the methoxy group in position 5 , and the ethylacetamide side chain in position 3 to be essential for high binding to both melatonin receptors