Salwa Mosad Mahmoud Soliman <br/><br/>
Synthesis, analysis and evaluation of New carbamate derivatives for enhanced brain delivery of baclofen /  
 تشييد و تحليل و تقييم مشتقات جديدة من كاربامات الباكلوفين لتحسين توصيل عقار الباكلوفين إلى المخ 
Salwa Mosad Mahmoud Soliman ; Supervised Hilde Spahn Langguth , Khaled AbouZid , Raimund Niess 
 - Cairo :   Salwa Mosad Mahmoud Soliman ,   2010 
 - 142 P. :   charts ;   30cm 
<br/><br/>Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry 
<br/><br/> The crntrally acting antispastic agent bactofen )R/S-4 amino-3-(4-chtorophenyl)butyric acid), was experienced to exhibit high therapeutic activity in certain severe spastic disorders. However, therapeutic levels are not reached in the central nervous system (CNS), unless the drug is administered intrathecally