TY  - GEN
AU  - Mona Mohamed Kamal
AU  - Abdelmoneim Mahmoud Osman , 
AU  - Mahmoud Mohamed Merzabani , 
AU  - Mohamed Taki Eldeen Khayyal , 
TI  - Effect of P - glycoprotein blockers on the bioavailability of paclitaxel in experimental animals / 
PY  - 2006///
CY  - Cairo : 
PB  - Mona Mohamed Kamal , 
KW  - P-glycoprotein
KW  - Paclitaxel
KW  - Verapamil
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology; Issued also as CD
N2  - Paclitaxel (Taxol) is an antineoplastic agent used to treat many types of cancer poor oral absorption and consequently poor bioavailability The poor oral bioavailability results mainly from the activity of the P - glycoprotein (P - gp) efflux pump multi - drug Cyclosporine (an immunosuppressive drug) and verapamil (a calcium channel blocker) were used in this study as examples of P - gp efflux pump blockers
UR  - http://172.23.153.220/th.pdf
ER  -