01993cam a2200349 a 4500 EG-GiCUC 20250223030836.0 130601s2013 ua dh f m 000 0 eng d EG-GiCUC eng EG-GiCUC eng Deposite Ph.D Cai01.11.29.Ph.D.2013.Mo.E Mona Farag Shabana Effect of solute carrier organic anion transporter 1B1 (SLCO1B1) and multiple drug resistance 1((MDR1) genotypes on lipid profile of atorvastatin - treated hypercholesterolemic Egyptian patients / Mona Farag Shabana ; Supervised Amal Anwar Mishriki , Ghada Abdelzaher Hashim , Sameh Wadie Ghali Bakhoum على صورة الدهون بالدم لمرضى مصريين مصابين بارتفاع الكوليسترول بالدم و يعالجون بعقار (أتورفاستاتين( (MDR1) و (SLCO1B1)تأثير الاشكال الجينية لجينى Cairo : Mona Farag Shabana , 2013 110P. : charts , facsimiles ; 25cm Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pharmacology The aim of the present study was to evaluate the effect of genetic polymorphisms of SLCO1B1 and MDR1 on the pharmacodynamics of atorvastatin which is the degree of improvement in the lipid profile of patients receiving atorvastatin . We studied 50 patients receiving atorvastatin in a dose of 40 mg once per day for a period of 4 weeks . We used the specific primers for restriction fragment length polymorphism Issued also as CD Atorvastatin Hypercholesterolemia MDRI Amal Anwar Mishriki , Supervisor Ghada Abdelzaher Hashim , Supervisor Sameh Wadie Ghali Bakhoum , Supervisor http://172.23.153.220/th.pdf Nazla Revisor Soheir Cataloger ddc TH 43081 43081 ddc 0 CUCL cl210 2024-02-11 Cai01.11.29.Ph.D.2013.Mo.E 01010110060706000 2023-09-22 00:00:00 TH ddc 0 CUCL cl2u8 2024-02-11 Cai01.11.29.Ph.D.2013.Mo.E 01020110060706000 2023-09-22 00:00:00 60706.CD CD