Effect of solute carrier organic anion transporter 1B1 (SLCO1B1) and multiple drug resistance 1((MDR1) genotypes on lipid profile of atorvastatin - treated hypercholesterolemic Egyptian patients
على صورة الدهون بالدم لمرضى مصريين مصابين بارتفاع الكوليسترول بالدم و يعالجون بعقار (أتورفاستاتين( (MDR1) و (SLCO1B1)تأثير الاشكال الجينية لجينى
Mona Farag Shabana
creator
Amal Anwar Mishriki
Supervisor
Ghada Abdelzaher Hashim
Supervisor
Sameh Wadie Ghali Bakhoum
Supervisor
text
theses
ua
Cairo
Mona Farag Shabana
2013
monographic
eng
110P. : charts , facsimiles ; 25cm
The aim of the present study was to evaluate the effect of genetic polymorphisms of SLCO1B1 and MDR1 on the pharmacodynamics of atorvastatin which is the degree of improvement in the lipid profile of patients receiving atorvastatin . We studied 50 patients receiving atorvastatin in a dose of 40 mg once per day for a period of 4 weeks . We used the specific primers for restriction fragment length polymorphism
specialized
Mona Farag Shabana ; Supervised Amal Anwar Mishriki , Ghada Abdelzaher Hashim , Sameh Wadie Ghali Bakhoum
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pharmacology
Issued also as CD
Atorvastatin
Hypercholesterolemia
MDRI
http://172.23.153.220/th.pdf
http://172.23.153.220/th.pdf
EG-GiCUC
130601
20250223030836.0
eng