Asmaa Samir Mohamed Nofal <br/><br/>
Expression of cyclin E2 and survivn in Egyptian acute leukemia patients /  
 التعبير عن سيكلين إي  و سيرفيفين فى المرضى المصريين الذين يعانون من سرطان الدم الحاد  
Asmaa Samir Mohamed Nofal ; Supervised Hanan Nour Rsalan , Manal Mohamed Makhlouf 
 - Cairo :   Asmaa Samir Mohamed Nofal ,   2013 
 - 234P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology 
<br/><br/> Acute leukemias are clonal expansions of uncommitted or partially committed haematopoietic precursor cells . Abnormalities in the control of programmed cell death (apoptosis) play important role in leukemogenesis . Survivin is a member of inhibitor of apoptosis proteins (IAP) family . It prevents apoptosis by blocking caspase activity . Dramatic overexpression of survivin was demonstrated in solid tumours of pancreas oesophagus lung as well as in leukemias and lymphomas 
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<br/><br/><label>Subjects--Index Terms: </label>Acute leukemias  Cyclin E2  Survivn