TY - BOOK AU - Asmaa Samir Mohamed Nofal AU - Hanan Nour Rsalan , AU - Manal Mohamed Makhlouf , TI - Expression of cyclin E2 and survivn in Egyptian acute leukemia patients / PY - 2013/// CY - Cairo : PB - Asmaa Samir Mohamed Nofal , KW - Acute leukemias KW - Cyclin E2 KW - Survivn N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology; Issued also as CD N2 - Acute leukemias are clonal expansions of uncommitted or partially committed haematopoietic precursor cells . Abnormalities in the control of programmed cell death (apoptosis) play important role in leukemogenesis . Survivin is a member of inhibitor of apoptosis proteins (IAP) family . It prevents apoptosis by blocking caspase activity . Dramatic overexpression of survivin was demonstrated in solid tumours of pancreas oesophagus lung as well as in leukemias and lymphomas UR - http://172.23.153.220/th.pdf ER -