Hebat Allah Salah Ahmad Yousuf <br/><br/>
Assessment of anti-schistosomal activity of mefloquine, in experimental schistosoma mansoni infection /  
 تقييم مدى فاعلية الميفلوكين على العدوى التجريبيه بالبلهارسيا المعويه 
Hebat Allah Salah Ahmad Yousuf ; Supervised Omaima Mohammed Aboushady , Soheir Sayed Mohammed Mahmoud , Dina Omar Helmy 
 - Cairo :   Hebat Allah Salah Ahmad Yousuf ,   2012 
 - 160 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Parasitology 
<br/><br/> It has been recently documented that the antimalarial drug mefloquine (MFQ) had interesting anti-schistosomal properties. This study aimed to assess the effect of single oral dose of mefloquine (400 mg/kg) and single oral dose of mefloquine (200 mg/kg) combined with praziquantel (500 mg/kg) on experimental Schistosoma mansoni infection. Mefloquine significantly reduced the worm burden, tissue egg load, number of liver granulomas and increased the percent of the dead ova within the granulomas 
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<br/><br/><label>Subjects--Index Terms: </label>Mefloquine Praziquantel S. mansoni