TY - BOOK AU - Hebat Allah Salah Ahmad Yousuf AU - Dina Omar Helmy , AU - Omaima Mohammed Aboushady , AU - Soheir Sayed Mohammed Mahmoud , TI - Assessment of anti-schistosomal activity of mefloquine, in experimental schistosoma mansoni infection / PY - 2012/// CY - Cairo : PB - Hebat Allah Salah Ahmad Yousuf , KW - Mefloquine KW - Praziquantel KW - S. mansoni N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Parasitology; Issued also as CD N2 - It has been recently documented that the antimalarial drug mefloquine (MFQ) had interesting anti-schistosomal properties. This study aimed to assess the effect of single oral dose of mefloquine (400 mg/kg) and single oral dose of mefloquine (200 mg/kg) combined with praziquantel (500 mg/kg) on experimental Schistosoma mansoni infection. Mefloquine significantly reduced the worm burden, tissue egg load, number of liver granulomas and increased the percent of the dead ova within the granulomas UR - http://172.23.153.220/th.pdf ER -