Heba Aly Mohamed Ateya <br/><br/>
The role of neoadjuvant aromatase inhibitors in ER / PR positive  HER-2 neu negative in postmenopausal females with locally advanced breast cancer /  
 دور مثبطات الارومازين فى العلاج ما قبل الجراحة فى حالات فى حالات سرطان الثدى المتقدم موضعيا فى السيدات بعد سن الياس ذوات مستقبلات الاستروجين / البروجستيرون الموجبة والهيرتو نيو السالبة 
Heba Aly Mohamed Ateya ; Supervised Heba M. Elzawahry , Nadia Mahmoud Mokhtar , Osman M. Mansour 
 - Cairo :   Heba Aly Mohamed Ateya ,   2013 
 - 188 P. ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology (Medical) 
<br/><br/> Background: In Egypt female breast cancer ranks as the first malignancy affecting females (37.5% in NCI Egypt). Approximately 20% to 25% of breast cancer patients present with locally advanced disease. Methods : this is a prospective study including fifty two female postmenopausal patients with newly diagnosed LABC, they receive 4 months of neoadjuvant aromatase inhibitor (letrozole) 2.5 mg daily followed by clinical and radiological evaluation, if they have at least partial response, they will be refered to surgery 
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<br/><br/><label>Subjects--Index Terms: </label>Aromatase inhibitors locally advanced breast cancer  Neoadjuvant