TY - BOOK AU - Heba Aly Mohamed Ateya AU - Heba Mohamed Elzawahry , AU - Nadia Mahmoud Mokhtar , AU - Osman Mohamed Mansour , TI - The role of neoadjuvant aromatase inhibitors in ER / PR positive HER-2 neu negative in postmenopausal females with locally advanced breast cancer / PY - 2013/// CY - Cairo : PB - Heba Aly Mohamed Ateya , KW - Aromatase inhibitors KW - locally advanced breast cancer KW - Neoadjuvant N1 - Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology (Medical); Issued also as CD N2 - Background: In Egypt female breast cancer ranks as the first malignancy affecting females (37.5% in NCI Egypt). Approximately 20% to 25% of breast cancer patients present with locally advanced disease. Methods : this is a prospective study including fifty two female postmenopausal patients with newly diagnosed LABC, they receive 4 months of neoadjuvant aromatase inhibitor (letrozole) 2.5 mg daily followed by clinical and radiological evaluation, if they have at least partial response, they will be refered to surgery UR - http://172.23.153.220/th.pdf ER -