Synthesis of some benzothiazole derivatives with expected anti- inflammatory activity /
تشيد بعض مشتقات البنزوثيازول المتوقع فاعليتها كمضادات للإلتهابات
Dina Hassan Hassan Dawood ; Supervised Kamelia Mahmoud Amin , Eman Mostafa Hassan Abbas
- Cairo : Dina Hassan Hassan Dawood , 2013
- 208 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry
This thesis deals with the synthesis of new benzothiazole derivatives bearing functionalized ary1 and bioactive heterocyole moieties at the 2nd and 3rd positions and some of the new target compound were subjected to in vivo anti - inflammatory analgesic and ulcerogenic screening. The most Pharmacologically active candidates were evaluated for their in vitro COX inhibition activites