Sara Abdelmgeed Hamed Elwakeel <br/><br/>
Possible modulation of inflammator mediatiors and hepatic fibrosis by an angiotensin II receptor blocker (ARB) in a rat model of CC14-induced liver injury /  
 التغيرات التى يمكن حدوثها للوسطاء الالتهابية والتليف الكبدى باستخدام مثبطات مستقبلات الانجيوتنسين 2 فى نموذج للجرذان المصابة بتليف كبدى ناجم عن استخدام رابع كلوريد الكربون 
Sara Abdelmgeed Hamed Elwakeel ; Supervised Ezz Eldin S. Eldenshary , Moushira Ibrahim Elsayed , Noha N. Nassar 
 - Cairo :   Sara Abdelmgeed Hamed Elwakeel ,   2013 
 - 90 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology 
<br/><br/> Hepatic fibrosis is defined as a wound healing response to liver injury characterized by the deposition of extracellular matrix (ECM). The duration of insult is a crucial parameter managing the extent of injury. Whereas an acute insult provokes transient changes and the normal hepatic architecture is regenerated, a more persistent injury results in sustained chronic inflammation and accumulation of ECM leading to progressive substitution of liver parenchyma by scar tissue 
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<br/><br/><label>Subjects--Index Terms: </label>Angiotensin II Hepatic fibrosis Liver injury