Mina Nabil Farid Morcos
Synthesis and pharmacological evaluation of novel monovalent and bivalent ligands for monomeric and dimeric melatonin receptors /
Mina Nabil Farid Morcos ; Supervised Darius P. Zlotos
- Cairo : Mina Nabil Farid Morcos , 2013
- 163 Leaves ; 30cm
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
Melatonin, the neurohormone secreted from the pineal gland, is responsible for the regulation of several physiological processes through interaction with two GPCRs, MT, and MTâ‚‚. The exact physiological role these two receptors is still unclear, and requires subtype selective melatonin ligands as pharmacological tools Recently a series of benzyloxy - substituted N-[3-(3-methoxyphenyl)propy) amides, exemplified by compound 24d