Salma Raouf Elmenawi <br/><br/>
Role of thymoquinone in alzheimer's disease targeting the cholinergic system /  
Salma Raouf Elmenawi ; Supervised Ola Ahmed Heikal , Nesrine S. Elsayed 
 - Cairo :   Salma Raouf Elmenawi ,   2013 
 - 125 Leaves :   charts , facsimiles ;   30cm 
<br/><br/>Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmacology and Toxicology 
<br/><br/> Alzheimer's disease (AD) is a neurodegenerative disorder characterized by extracellular deposition of aggregated Ý amyloid protein (AÝ). Recently, correlation between nicotinic reseptors (nACHRs) dysfunction, neurodegeneration and cognitive deficits was shown in AD. nACHRs have protective role against AÝ toxicity while chronic inflammation damages cholinergic neurons and contributes to neurodegeneration