TY  - BOOK
AU  - Noura Mohamed Salah Eldin Riad
AU  - Darius P. Zlotos , 
TI  - Novel melatonergic ligands with potential MT₁⁻ selectivity : : Synthesis and pharmacological evaluation / 
PY  - 2013///
CY  - Cairo : 
PB  - Noura Mohamed Salah Eldin Riad , 
N1  - Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
N2  - Numerous functions of the neurohormone melatonin are mediated through activation of the G - protein - coupled receptors MT₁⁻ and MT₂. Elucidation of the pathophysiological function of the MT₁ receptor has been hampered mainly by the limited availability of selective full agonist and full antagonist for this receptor subtype. Design and synthesis of selective MT₁ receptor ligands with higher affinity and selectivity may contribute to better understanding of physiological functions mediated by MT₁ receptors
UR  - http://172.23.153.220/th.pdf
ER  -