TY  - BOOK
AU  - Mona Mohsen Ahmed Abouelghar
AU  - Naglaa Mohamed Kholoussi , 
AU  - Noha Mohamed Hosny Shahin , 
AU  - Safaa Mostafa Elkaraksy , 
TI  - Study of Tumor Necrosis Factor-Related Apoptosis Inducing Ligand (TRAIL) mRNA Expression in Patients with Systemic Lupus Erythematosus/ 
PY  - 2014///
CY  - Cairo : 
PB  - Mona Mohsen Ahmed Abouelghar , 
KW  - Real time PCR
KW  - Systemic lupus erythematosus
KW  - Tumor necrosis factor related apoptosis inducing ligand
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology; Issued also as CD
N2  - TRAIL (APO-2 ligand) is a transmembrane (type II) glycoprotein which also belongs to the TNF superfamily. TRAIL triggers apoptosis through interaction with the death receptors Death Receptor (DR4) (TRAIL-R1) and (DR5) (TRAIL-R2). There are several indications that TRAIL could be involved in the pathophysiology of autoimmune diseases in general and systemic lupuserythematosus (SLE) in particular. The aim of this study was to investigate TRAIL m RNA expression levels in peripheral blood mononuclear cells(PBMCs) from patients with SLE and to study the association between the results and various clinical and laboratory data of the patients in order to assess the possible role of TRAIL in SLE pathogenesis and its relation to disease activity
UR  - http://172.23.153.220/th.pdf
ER  -