TY - BOOK AU - Maram Mourad Hassan Mansour AU - Boushra Mohammed Elhoussieny Yousef , AU - Magdy Ibrahim Mohammed , TI - Formulation of an anti - inflammatory drug as fast dissolving tablets / PY - 2014/// CY - Cairo : PB - Maram Mourad Hassan Mansour , KW - Direct compression KW - Fast dissolving tablets KW - Ketroloac tromethamine N1 - Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics; Issued also as CD N2 - Ketorolac tromethamine is a potent non steroidal anti - inflammatory drug (NSAID) that is widely used in treatment of moderate to sever pain. It was reported that ketorolac produces its analgesic activity via inhibition of prostaglandin synthesis. However, due to its high potency, it has been proposed that this drug has another mechanism of action such as nitric oxide release. ketorolac tromethamine fast dissolving tablets were developed using direct compression method with the addition of superdisintegrants. Three types of superdisintegrants namely croscaramellose sodium, crospovidone and sodium starch glycolate were incorporated in tablets formulation UR - http://172.23.153.220/th.pdf ER -