Noura Samir Karawya

Event related potentials in bipolar disorder with co morbid anxiety disorder / الجهد المستثار لاضطرابات ثنائي القطب المصاحب باضطرابات القلق Noura Samir Karawya ; Supervised Mohamed Yousry Abdelmohsin , Heba Fathy Abdelreheem , Reem Atef Elhadidy - Cairo : Noura Samir Karawya , 2014 - 185 P. : charts ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Neuropsychiatry

Objective: This study measures the suppression in P50, N100, and P200 waves in auditory evoked potential for bipolar disorder patients with and without comorbid anxiety disorder, and finding a correlation with impulsivity. Method:3 groups were compared in the study: 30 bipolar disorder patients, 30 bipolar disorder patients with comorbid anxiety disorder, and 30 healthy subjects as control.Auditory evoked potential was tested using the paired click paradigm; also an impulsivity score was done after full psychiatric examination. Results:Bipolar disorder patients showed higher suppression in P50, N100, and P200 waves than bipolar disorder patients with comorbid anxiety; which is also higher than controls, and impulsivity scores were higher in bipolar disorder patients with comorbid anxiety. Conclusion: auditory evoked potential may work as an indicative tool for measuring the severity of bipolar disorder and that anxiety disorders increase impulsivity in bipolar disorder patients



Anxiety disorder comorbidity Auditory evoked potential Bipolar disorder