Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Neuropsychiatry
Objective: This study measures the suppression in P50, N100, and P200 waves in auditory evoked potential for bipolar disorder patients with and without comorbid anxiety disorder, and finding a correlation with impulsivity. Method:3 groups were compared in the study: 30 bipolar disorder patients, 30 bipolar disorder patients with comorbid anxiety disorder, and 30 healthy subjects as control.Auditory evoked potential was tested using the paired click paradigm; also an impulsivity score was done after full psychiatric examination. Results:Bipolar disorder patients showed higher suppression in P50, N100, and P200 waves than bipolar disorder patients with comorbid anxiety; which is also higher than controls, and impulsivity scores were higher in bipolar disorder patients with comorbid anxiety. Conclusion: auditory evoked potential may work as an indicative tool for measuring the severity of bipolar disorder and that anxiety disorders increase impulsivity in bipolar disorder patients