TY - BOOK AU - Marwa Khaled Sayed Abdelshafy AU - Fatina Ibrahim Fade , AU - Hafez Mahmoud Bazaraa , AU - Mohamed Gamal Shouman , TI - Visfatin as a marker of endothelial dysfunction in pediatric kidney transplant recipients / PY - 2014/// CY - Cairo : PB - Marwa Khaled Sayed Abdelshafy , KW - Chronic kidney disease KW - End-stage renal disease KW - Endothelial dysfunction N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics; Issued also as CD N2 - Kidney transplantation is treatment of choice for pediatric end stage renal disease. In this study, Visfatin serum level has been evaluated (in 30 hemodialysis patients, 36 transplant recipients, and 30 controls), as a measure for endothelial dysfunction, and has been compared to brachial artery flow mediated dilatation. Visfatin level in transplant recipients [median (IQR) of 4 (3.5-5.8) ng/ml], was significantly (p<0.0001) lower than the hemodialysis group [median (IQR) of 65 (30-70) ng/ml], and not significantly different from controls [median (IQR) of 5 (2.4-6) ng/ml)]. Flow mediated dilatation was also better in transplant recipients. No direct statistical correlation could be reached between Visfatin level and flow-mediated dilatation. Endothelial dysfunction is significantly improved in transplant recipients UR - http://172.23.153.220/th.pdf ER -