TY  - BOOK
AU  - Lubna Ahmed Abdulrahman Kormod 
AU  - Ahmed Emad Elgindy , 
AU  - Maha Abdelmoneim Hegazy , 
AU  - Mohamed Abdelkawy , 
TI  - Analysis of selected  antispasmodic compounds / 
PY  - 2014///
CY  - Cairo : 
PB  - Lubna Ahmed Abdulrahman Kormod  , 
KW  - HPLC/UV
KW  - Simultaneous analysis
KW  - Stability indicating methods
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Analytical Chemistry; Issued also as CD
N2  - The thesis consists of three parts. Part I: It includes a brief introduction to selected  antispasmodic compounds. Part II: This part includes stability indicating methods for  determination of mebeverine hydrochloride. Degradation of mebeverine was studied under acidic  and alkaline stress conditions and the degradation products formed after complete degradation  were identified using Infra Red and Mass spectroscopic techniques. Determination of  mebeverine in the presence of its degradation products was achieved using High Performance  Liquid Chromatography coupled to Ultra Violet and Fluorescence detectors. Ultra Performance  Liquid Chromatography coupled to Mass Spectrometric detection was used. Several  spectrophotometric methods were used, which are the mean centering of ratio spectra method,  the extended ratio subtraction method followed by direct spectrophotometry, and first derivative  calculation by numerical differentiation and continuous wavelet transforms method.  Synchronous Fluorescence Spectroscopic technique was utilized through the calculation of  double divisor of ratio spectra by numerical differentiation and continuous wavelet transforms
UR  - http://172.23.153.220/th.pdf
ER  -