TY  - BOOK
AU  - Mohamed Abdulhay Ahmed Masoud
AU  - Lobna Abdelgawad Mansour , 
AU  - Mariam Onsy Farag , 
AU  - Marian Yousry Fahmy , 
TI  - The influence of immunoglobulin IgG Fc - receptor polymorphisms on susceptibility to guillain - barre{u00B4} syndrome / 
PY  - 2014///
CY  - Cairo : 
PB  - Mohamed Abdulhay Ahmed Masoud , 
KW  - FcÞR
KW  - Guillain barre{u00B4} syndrome
KW  - Polymorphism
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics; Issued also as CD
N2  - Macrophages and ganglioside-specific immunoglobulin G (IgG) are involved in the pathogenesis of guillain - barre{u00B4} syndrome (GBS). Leukocyte IgG receptors (FcÞR) confer potent cellular effector functions to the specificity of IgG. The efficacy of IgG - mediated cellular inflammatory responses is determined by functional polymorphisms of three FcÞR subclasses (FcÞRIIA: H131/R131; FcÞRIIIA: V158 / F158; FcÞRIIIB: NA1/NA2). FcÞR genotype distributions were determined in some cohorts of GBS patients and controls. The purpose of our study was mainly to investigate the role of the host immunogenetic factors like high affinity FcÞR polymorphism in the development of GBS compared to controls and their association with commonly described antecedent infections, electrophysiological subtypes, severity and outcome of GBS
UR  - http://172.23.153.220/th.pdf
ER  -