02710cam a2200349 a 4500 EG-GiCUC 20250223031351.0 151210s2015 ua dh f m 000 0 eng d EG-GiCUC eng EG-GiCUC eng Deposite M.Sc Cai01.11.27.M.Sc.2015.Sh.E Shimaa Mohamed Ahmed Abdelsalam Evaluation of CD10 expression in urothelial bladder carcinoma : Histopathological and immunohistochemical study / Shimaa Mohamed Ahmed Abdelsalam ; Supervised Ahmed Mahmoud Abdelaziz , Sahar Abdelhamed Tabak , Amira Mohammed Bassam التعبير عن ال"سى دى١٠" و علاقته بسرطان المثانه البوليه : دراسة هستوباثولوجية و هستومناعية Cairo : Shimaa Mohamed Ahmed Abdelsalam , 2015 121 P. : charts , facsimiles ; 25cm Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pathology The aim of this work is to study the immunohistochemical expression of CD10 in urothelial carcinoma of the urinary bladder and its possible prognostic value. Forty one radical cystectomy specimens; collected from the pathology department, Faculty of Medicine, Cairo University. Two slides were prepared from each paraffin embedded tumor block, one slide was stained for Hematoxylin and eosin (H and E) staining for histopathological reassessment and the other positively charged slide was stained immunohistochemically by CD10 monoclonal antibody. The immunohistochemical demonstration of the immunohistochemical marker was accomplished by using immunoperoxidase method. Staining of the cell membrane and/or cytoplasm was considered positive expression. A semi - quantitative scoring based on the percentage of positive cells was performed. Positive CD10 immunohistochemical expression was found to be significantly correlated with patients' age, tumor size, presence of squamoid differentiation and positive lymph node metastasis. Also there was significant correlation between CD10 scoring and presence of extravesical extension as well as vascular invasion. No significant correlation between CD10 immunohistochemical expression and tumor stage could be detected Issued also as CD CD10 Urinary bladder Urothelial carcinoma Ahmed Mahmoud Abdelaziz , Supervisor Amira Mohammed Bassam , Supervisor Sahar Abdelhamed Tabak , Supervisor http://172.23.153.220/th.pdf Nazla Revisor Samia Cataloger ddc TH 53854 53854 ddc 0 CUCL cl210 2024-02-11 Cai01.11.27.M.Sc.2015.Sh.E 01010110067135000 2023-09-22 00:00:00 TH ddc 0 CUCL cl2u8 2024-02-11 Cai01.11.27.M.Sc.2015.Sh.E 01020110067135000 2023-09-22 00:00:00 67135.CD CD