TY  - BOOK
AU  - Hanzada Tawfik Mohamed Noor Eldin 
AU  - Abdelgawad Hashem , 
AU  - Aymen Samir Yassin , 
AU  - Yasser Elmohammady Ragab , 
TI  - Patterns of colonization and infection among methicillin resistant staphylococcus aureus local isolates from intensive care units / 
PY  - 2015///
CY  - Cairo : 
PB  - Hanzada Tawfik Mohamed Noor Eldin , 
KW  - Colonized MRSA
KW  - Multi Locus Sequence Typing
KW  - Nosocomial MRSA
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Microbiology and Immunology; Issued also as CD
N2  - Methicillin-resistant Staphylococcus aureus (MRSA) is characterized by its resistance  to almost all beta lactams and other antibiotics belonging to various classes. The ability of  MRSA to spread in hospitals, particularly in intensive care units (ICUs) has posed a major  challenge for infection control worldwide. Based on their localization in the human body,  hospital-acquired MRSA (HA-MRSA) can be classified into colonized or infectious. The aim  of this work is to conduct an analysis to differentiate between these two classes.  From a total of 100 isolates collected from the ICU of two major Egyptian hospitals,  49 isolates were confirmed as MRSA, out of which, 30 isolates were infectious and 19 were  colonized. Biofilm formation showed that infectious isolates had significantly higher biofilm  formation ability. The antibiogram revealed that each type of isolates had its own resistance  pattern; MIC of a number of infectious isolates showed an MIC creep which can lead to  future resistance. 16SrRNA sequencing confirmed the identity of several isolates; ERIC PCR  typing classified the isolates into several groups. Multi locus sequence typing confirmed the  relation between the isolates obtained from ERIC typing and showed the origin of some of  the isolates. The resistance gene mecA was absent in one of the colonized isolates
UR  - http://172.23.153.220/th.pdf
ER  -