TY - BOOK AU - Mohamed Osama Mostafa AU - Dalia Hussein Elrouby , AU - Hend Mohamed Wagih , TI - Immunohistochemical expression of phosphatidyl-inositol-30 kinase (PI3K)/Akt2 in oral epithelial dysplasia and squamous cell carcinoma / PY - 2014/// CY - Cairo : PB - Mohamed Osama Mostafa , KW - Akt (PKB) KW - Oral cancer KW - Protein kinase B N1 - Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine- Department of Oral Pathology; Issued also as CD N2 - Oral cancer is one of the most common cancers worldwide and is thought to arise from progressive dysplastic changes of the oral squamous epithelium. Thirty-six paraffin blocks were investigated in this study including fifteen premalignant dysplastic lesions and fifteen OSCC. In addition, six specimens from normal tissue were used as a control. Slides were immunostained by the monoclonal mouse anti-human Akt2 antibody. The immunostained sections were analyzed by an image analyzer computer system using the software LeciaQwin 500.The area percent of the positive nuclear and cytoplasmic immunoreaction was measured in normal oral tissue, in oral dysplastic lesions and in different grades of SCC UR - http://172.23.153.220/th.pdf ER -