TY  - BOOK
AU  - Rasha Hossam Eldin Mahfouz
AU  - Hala Mohamed Lotfy , 
AU  - Naglaa Abdelrahman Mosaad , 
AU  - Rasha Mohamad Hosny Shahin , 
TI  - Study of serum syndecan-1 levels in juvenile systemic lupus erythematosus (JSLE) Egyptian patients / 
PY  - 2016///
CY  - Cairo : 
PB  - Rasha Hossam Eldin Mahfouz , 
KW  - JSLE
KW  - Lupus nephritis
KW  - SLEDA{u2160}-2K score
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics; Issued also as CD
N2  - Systemic Lupus Erythematosus (SLE) is characterized by loss of B-cell tolerance so Syndecan-1  (SDC-1) which is expressed on plasma cells derived from B-cells is thought to play a role in SLE . This is a cross-sectional study conducted on 60 JSLE patients and 30 healthy controls . Serum SDC-1 level was measured using ELISA technique and correlated with different clinical  and laboratory data as well as SLEDAI-2K , renal SLEDAI , renal activity scores . Our results  showed that Syndecan-1 is significantly higher in SLE patients compared with controls . Also, it  has positive correlation with activity scores so it can be used as a marker for disease activity and  renal activity in JSLE patients
UR  - http://172.23.153.220/th.pdf
ER  -