Bishoy Ibrahim Halim Khalifa <br/><br/>
Serum ferritin level as a marker of disease activity and renal involvement in Egyptian children with Juvenile Systemic Lupus Erythematosus /  
 مستوى الفيريتين فى الدم كعلامة من علامات نشاط المرض و تأثر الكلى فى حالات الذئبة الحمراء الصبيانى في الأطفال المصريين 
Bishoy Ibrahim Halim Khalifa ; Supervised Samia Salah Eldin Mahmoud , Yomna Mohamed Farag , Doaa Mohamed Geith 
 - Cairo :   Bishoy Ibrahim Halim Khalifa ,   2016 
 - 103 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics 
<br/><br/> Juvenile systemic lupus erythematosus (JSLE) is a multi-system autoimmune disease associated with formation of auto-antibodies. Higher serum ferritin levels have been observed in inflammatory conditions as SO JIA & MAS. This study assesses its use as a marker of disease activity & lupus nephritis in JSLE. This is a cross-sectional study conducted on 48 JSLE  patients  and 43 healthy controls. Serum ferritin level was measured using ELISA technique. Our results showed that serum ferritin is significantly higher in JSLE patients compared with controls. Also, it has positive correlation with SLEDAI-2K, renal SLEDAI,SLICC renal activity score, C3 and anti ds DNA level. Therefore, serum ferritin can be used as a marker for disease activity& renal activity 
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<br/><br/><label>Subjects--Index Terms: </label>JSLE Lupus nephritis Serum ferritin