TY - BOOK AU - Bishoy Ibrahim Halim Khalifa AU - Doaa Mohamed Geith , AU - Samia Salah Eldin Mahmoud , AU - Yomna Mohamed Farag , TI - Serum ferritin level as a marker of disease activity and renal involvement in Egyptian children with Juvenile Systemic Lupus Erythematosus / PY - 2016/// CY - Cairo : PB - Bishoy Ibrahim Halim Khalifa , KW - JSLE KW - Lupus nephritis KW - Serum ferritin N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics; Issued also as CD N2 - Juvenile systemic lupus erythematosus (JSLE) is a multi-system autoimmune disease associated with formation of auto-antibodies. Higher serum ferritin levels have been observed in inflammatory conditions as SO JIA & MAS. This study assesses its use as a marker of disease activity & lupus nephritis in JSLE. This is a cross-sectional study conducted on 48 JSLE patients and 43 healthy controls. Serum ferritin level was measured using ELISA technique. Our results showed that serum ferritin is significantly higher in JSLE patients compared with controls. Also, it has positive correlation with SLEDAI-2K, renal SLEDAI,SLICC renal activity score, C3 and anti ds DNA level. Therefore, serum ferritin can be used as a marker for disease activity& renal activity UR - http://172.23.153.220/th.pdf ER -