TY  - BOOK
AU  - Marwa Soliman Gaman Salama
AU  - Rafat Milad Mohareb , 
TI  - Synthesis and anti tumor evaluation of Heterocyclic compounds synthesized from Ý-diketone and active methylene derivatives / 
PY  - 2016///
CY  - Cairo : 
PB  - Marwa Soliman Gaman Salama , 
KW  - Benzimidazole compounds
KW  - Heterocycles
KW  - Synthesis
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry; Issued also as CD
N2  - In this work the reaction of O-phenylenediamine (1) with diethylmalonate (2) in an oil bath at 120 {u00B0}C gave ethyl 2- (1H-benzo [d] imidazol-2-yl) acetate (3). Compound 3 was used in many acyclic and heterocyclic reactions. The latter products underwent a series of heterocyclization reactions to yield pyrazole, thiophene, pyridine and coumarin derivatives. The antitumor evaluations of the newly synthesized products against three cancer cell lines were measured
UR  - http://172.23.153.220/th.pdf
ER  -