TY  - BOOK
AU  - Asmaa Salah eldin Ahmed Fathallah
AU  - Amany Ibrahim Mohamed , 
AU  - Mona Mamdouh Hassan , 
AU  - Noha Arafa Mohamed , 
TI  - Risk factors of ketoacidosis at the diagnosis of diabetes mellitus / 
PY  - 2016///
CY  - Cairo : 
PB  - Asmaa Salah eldin Ahmed Fathallah , 
KW  - Diabetes
KW  - Diabetic ketoacidosis
KW  - Risk factors
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics; Issued also as CD
N2  - Introduction: Diabetes Mellitus (DM) is a metabolic disorder of glucose  homeostasis and is one of the most common endocrine diseases in children  worldwide. Diabetic ketoacidosis (DKA) is a common serious acute complication in children with DM. Its incidence in children at the onset of DM remains high,  with approximately one-third presenting with mild DKA and one-sixth with  moderate or severe DKA. Multiple factors affect the risk of developing DKA at  the onset of DM in children. Aim of the study: to identify and analyze the risk factors associated with the development of ketoacidosis at the diagnosis of new cases with DM.  Methods: Ninety nine children (53 DKA and 46 hyperglycemia) , age range  from 1 month to 13 years, diagnosed with newly diagnosed diabetes, referred and managed at DEMPU in Children{u2019}s Hospital, Cairo University. Results: Classic symptoms (polyuria, polydipsia and weight loss) were the  most common symptoms (93.8% & 92%) preceding the diagnosis; and diabetic  ketoacidosis was present in 53.5%. Positive family history of diabetes was recorded in 54.5%, most of them with T2DM, but with no significant difference  in the presentation. Delayed and missed diagnosis was recorded in 79.8% &  53.5% respectively, with significant difference affecting the presentation. Time lapse between diagnosis and start of insulin was found to be the most significant  risk factor for developing DKA at diagnosis
UR  - http://172.23.153.220/th.pdf
ER  -