Aya Elsayed Elsayed Khedr <br/><br/>
Uses of nitriles and carbonyl compounds in the synthesis of biologically active heterocyclic compounds /  
 استخدامات مركبات النيتريل و الكاربونيل لتحضير المركبات غير متجانسة الحلقة ذات النشاط البيولوجى 
Aya Elsayed Elsayed Khedr ; Supervised Raafat Milad Mohareb 
 - Cairo :   Aya Elsayed Elsayed Khedr ,   2016 
 - 139 P. :   charts , photographs ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry 
<br/><br/> In this work the reaction of ethylacetoacetate (1) with Ü-naphthylamine (2) gave the N-(Naphthalen-1-yl)-3-oxobutanamid (3). The latter products underwent a series of heterocyclization reactions to yield pyridine, pyran, thiophene and pyrazole derivatives. The antitumor evaluations of the newly synthesized products against three cancer cell lines were measured 
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<br/><br/><label>Subjects--Index Terms: </label>1,3-dicarbonyl compounds Heterocycles Synthesis