01360cam a2200229 a 4500003000900000005001700009008004100026040002800067041000800095100003900103245023500142260005900377300004800436502014100484520031400625653002500939653002900964653003000993700003801023700003601061856003301097EG-GiCUC20250223031800.0170812s2016    ua dh  f m    000 0 eng d  aEG-GiCUCbengcEG-GiCUC0 aeng0 aEngy Ahmed Hesham Salah Edin Fadel10aEffect of pyrroloquinoline quinone on mitochondrial biogenesis and its derermination in a neuroinflammatory Alzheimer's disease Mouse model / cEngy Ahmed Hesham Salah Eldin Fadel ; Supervised Reham Abdelkader , Rasha Sayed Hanafi  aCairo : bEngy Ahmed Hesham Salah Eldin Fadel , c2016  a115 Leaves : bcharts , facsimiles ; c30cm  aThesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmacology and Toxicology  aAlzheimer's disease (AD) treatment is a challenge due to the fact that pathogenesis of the disease is very comlicated and not well understood. Several studies show that mitochondrial dysfunction plays an importtant role im AD. reduced mitochondria number in hippocampal in brains from AD patients was reported 4aAlzheimer's disease  4aMitochondrial biogenesis 4aPyrroloquinoline quinone 0 aRasha Sayed Hanafi , esupervisor0 aReham Abdelkader , esupervisor  uhttp://172.23.153.220/th.pdf