TY  - BOOK
AU  - Sally Farouk Fathy Elgendy 
AU  - Ali Mohamed Taha , 
AU  - Khaled Gamal Abualenen , 
AU  - Noha Mahmoud Khalil , 
TI  - Assessment of retinal ganglion cell complex thickness in diabetic patients before and after intravitreal injection ofanti-vegf agents (ranibizumab) by spectral domain O.C.T : 
PY  - 2017///
CY  - Cairo : 
PB  - Sally Farouk Fathy Elgendy , 
KW  - Diabetic Macular Edema
KW  - Intravitreal  Ranibizumab Injection
KW  - Retina
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Ophthalmology; Issued also as CD
N2  - Purpose:To evaluate retinal ganglion cell complex thickness  before and after Ranibizumab intravitreal injection in patients of diabetic macular edema using spectral domain optical coherence tomography (SD-OCT) scans.Methods : prospective interventional case series ,Thirty- three eyes of 27 patientswith diabetic macular edema were imaged by spectral domain optical coherence tomography (SD-OCT) before receiving Ranibizumabintravitreal injection,4 weeks and 2 months after injection . thickness changes in retinal ganglion cell complex after 3 months follow up period were quantitatively analyzed and correlated. Results:There is a statistical significant decrease in Average Retinal ganglion cell complex thicknessas well as the superior and inferior ganglion cell thickness ( P value <0.001, 0.000 and 0.000 ) respectively. The correlation between ganglion cell complex thickness values and duration of diabetes mellitus  shows no statistical significant  relation .Conclusion :  Intra-vitreal   Ranibizumab injection cause significant reduction in the Average, superior,inferior  thickness of retinal ganglion cell layer in diabetic patients along 3 months follow up period ,with negative correlation between duration of diabetes and ganglion cell complex thickness parameters.Further studies with larger sample,longer follow-up and greater number of injections ,are warranted
UR  - http://172.23.153.220/th.pdf
ER  -