Alaa Rizk Sanad Ibrahim Leila <br/><br/>
Design , synthesis of symmetric molecules as potential anti-HCV agents /  
 تصميم وتحضير الجزيئات المتماثلة المضادة لفيروس سي 
Alaa Rizk Sanad Ibrahim Leila ; Supervised Ashraf H. Abadi , Mohammad Abdelhalim 
 - Cairo :   Alaa Rizk Sanad Ibrahim Leila ,   2017 
 - 101 Leaves :   charts , facsimiles ;   30cm  
<br/><br/>Thesis (M.Sc.) - German University - Faculty of  Postgraduate Studies and Scientific Research  - Department of Pharmaceutical Chemistry  
<br/><br/> Until recently, the standard therapy for HCV treatment has been a combination of interferon Ü (IFNÜ) and ribavirin (RBV) which has severe side effects and contraindications. Cure rates reported for this combination therapy were about 50%¹² therefore, direct-acting antivirals (DAAs) were developed to target viral proteins that are crucial for the HCV lifecycle