Eman Ahmed Hafez Abdelaal <br/><br/>
Design and synthesis of novel aryl thiazolidine carboxylic acid amide derivatives as anticacer agents /  
 تصميم وتشييد مشتقات جديدة من الثازوليدين حامض الكاربوكسيلك أميد كمضادات للسرطان  
Eman Ahmed Hafez Abdelaal ; Supervised Ashraf H. Abadi , Mohammad Abdelhalim 
 - Cairo :   Eman Ahmed Hafez Abdelaal ,   2017 
 - 101 Leaves :   charts , facsimiles ;   30cm  
<br/><br/>Thesis (M.Sc.) - Garman University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chamistry 
<br/><br/> Lysophosphatidic acid (LPA) ia a potent lipid mediator that acts as ligand activator of many signaling pathways. Autotaxin (ATX) is the main enzyme responsible for the production of LPA in our bodies. LPA has been found to have a key role in many pathological disorders including cancer