Amira Atef Ahmed Mohammed Helwa <br/><br/>
Design and synthesis of pyrimidine derivatives as potential anticancer and antimicrobial agents /  
 تصميم وتشييد مشتقات البيريمدين كمضادات ممكنه للسرطان والميكروبات  
Amira Atef Ahmed Mohammed Helwa ; Supervised Afaf Kamal Eldin Elansary , Azza Taher Taher Shalaby , Sahar Mahmoud Abouseri 
 - Cairo :   Amira Atef Ahmed Mohammed Helwa ,   2018 
 - 118 P. :   charts ;   25cm  
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Organic Chemistry 
<br/><br/> The present work is concerned with the synthesis of certain pyrimidinone-5-carbonitriles, morpholinopyrimidine-5-carbonitrile derivatives with the detailed procedures. Additionally, the thesis includes the characterization of new compounds as well as the structure activity correlation and conclusion of the results of anticancer and antimicrobial screening 
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<br/><br/><label>Subjects--Index Terms: </label>Anticancer  Morpholinopyrimidine-5-carbonitrile  Pyrimidinone-5-carbonitrile