TY  - BOOK
AU  - Mahmoud Esmail Mohamed Alalfy
AU  - Jehan Mohamed Alsharnoubi , 
AU  - Mohamed Amr Hussein Elnoury , 
AU  - Osama Mahmoud Azmy , 
TI  - Laser based detection of maternal plasma cell free fetal DNA for early fetal sex determination / 
PY  - 2018///
CY  - Cairo : 
PB  - Mahmoud Esmail Mohamed Alalfy , 
KW  - DNA
KW  - Maternal plasma
KW  - Sex determination
N1  - Thesis (Ph.D.) - Cairo University - National Institute of Laser - Department of Laser Application in Medical and Biological; Issued also as CD
N2  - Enhancement of DNA detection assays increases the use of  non-invasive prenatal diagnosis that consequently enhances the supervision plan of pregnant woman  with genetic disorder that could have an expected babies with this disorder. Aim of work: current work was planned to examine plasma of  pregnant women starting from 6 th week of the pregnancy for Cell-free fetal DNA,  to determine embryonic sex type with consequent prospect of  detection of fetal anomalies such as sex-linked genetic abnormalities . Method: samples collected from 6 th  week  till 11 th  week  of pregnancy according to pregnancy age   and tested using Real time PCR for determination of fetal sex Results: testing of samples resulted   in detection of   fetal  sex starting from  6th week and the later  the gestational age ,the better the  result  for detection of fetal  sex . all results  were confirmed by Ultrasound  scan  and  neonatal outcome. Testing results revealed PCR detection for 58 males and 92 females with confusion in one  fetus  due to non identical twins
UR  - http://172.23.153.220/th.pdf
ER  -