TY  - BOOK
AU  - Amr Muhammed Rakha
AU  - Laila Ahmed Rashed , 
AU  - Rehab Shehata Abdelhady , 
AU  - Sawsan Farouk Helal , 
TI  - Oxidative stress status and dna damage on occupational exposure to polycyclic aromatic hydrocarbons among coal tar workers / 
PY  - 2018///
CY  - Cairo : 
PB  - Amr Muhammed Rakha , 
KW  - 1-Hydroxypyrene
KW  - Coal tar production
KW  - Polycyclic aromatic hydrocarbons
N1  - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Industrial and Occupational Disease; Issued also as CD
N2  - Introduction: Polyaromatic hydrocarbons (PAHs) are of occupational and environmental concern as they are toxic, carcinogenic, mutagenic, and/or teratogenic (causing birth defects) and even are probable human carcinogens.Objective: To assess the health effects of occupational exposure to PAHs on DNA damage and oxidative stress. Methods: A group of 40 coal tar workers and another 40 matched control were subjected to full history and clinical examination,estimation of 1-hydroxypyrene (1-OHPyrene) level in urine, Benzopyrene-DNA adducts, oxidative stress enzymes (Superoxide dismutase and glutathione peroxidase),Cytochrome P450 and Complete blood picture. Results: Statistically significant higher level of 1-OHPyrene, DNA adducts and lower levels of superoxide dismutase and glutathione peroxidase were detected among the exposed workers compared to the control group. Conclusion: oxidative stress and DNA damage might be among the hazards that can be attributed to occupational exposure to PAHs among coal tar workers
UR  - http://172.23.153.220/th.pdf
ER  -