01868cam a2200253 a 4500003000900000005001700009008004100026040002800067041000800095100003100103245018600134246011900320260004900439300003200488502008700520520081700607530002201424653001601446653003301462653001201495700003801507700003601545856003301581EG-GiCUC20250223032311.0190611s2018    ua d   f m    000 0 eng d  aEG-GiCUCbengcEG-GiCUC0 aeng0 aRiham lutfi Mohamed Sayed 14aThe effect of disease severity on growth in children and adolescents with Familial Mediterranean Fever / cRiham lutfi Mohamed Sayed ; Supervised Heba Taher Othman , Noha Musa Azzab15aتأثير شدة المرض على نمو أطفال مرضى حمى البحر الأبيض المتوسط  aCairo : bRiham lutfi Mohamed Sayed , c2018  a119 P. : bcharts ; c25cm   aThesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics  aThe study  aimed   to evaluate the effect of disease severity on growth in children and adolescents with Familial  Mediterranean Fever . It was a cross sectional study including 100 FMF patients divided into 2 groups ( 50 respondents and 50 resistant) according to FMF 50 score. Both groups were studied regarding (demographic data, clinical manifestations, disease severity, colchicine therapy, anthropometric measurements, laboratory findings and type of gene mutation.Results showed statistically significant difference between two groups in height SDS, weight SDS, BMI, height velocity and height velocity SDS (p<0.001) Inflammatory markers (CRP and ESR) as well were higher in resistant group. Our study concluded that colchicine respondents had better growth velocity than colchicine resistant FMF patients  aIssued also as CD 4aColchicine  4aFamilial Mediterranean fever 4aGrowth 0 aHeba Taher Othman , eSupervisor 0 aNoha Musa Azzab , eSupervisor   uhttp://172.23.153.220/th.pdf