Mohamed Ahmed Obaya

Early versus delayed administration of norepinephrine in patients with septic shock and use of oral midodrine in weaning off norepinephrine in these patients / إعطاء النورادرينالين فى وقت مبكر مقابل تأخر اعطاؤه لمرضى الصدمة الإنتانية وأستخدام الميدودرين بالفم فى الفطام من النورادرينالين فى هؤلاء المرضى Mohamed Ahmed Obaya ; Supervised Alia Abdelfattah , Randa Ali , Moemen Yehia - Cairo : Mohamed Ahmed Obaya , 2019 - 123 P. : charts ; 25cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Critical Care Medicine

edefine sepsis as agreed upon by The Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM) as the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) (Singer M., et al. 2016). Sepsis: 2life-threatening organ dysfunction caused by a dysregulated host response to infection.3 End organ damage is identified as an acute change in total Sequential [Sepsis-related] Organ Failure Assessment score (SOFA) 2 (Rhodes A., et al 2016). Septic shock: A subset of sepsis 2in which circulatory, cellular, and metabolic abnormalities are associated with a greater risk of mortality than with sepsis alone. These patients can be clinically identified by a vasopressor requirement to maintain a MAP 65mmHg and serum lactate >2mmol/L in the absence of hypovolemia (Singer M., et al 2016)



Midodrine Norepinephrine Septic Shock