02310cam a2200337 a 4500 EG-GiCUC 20250223032326.0 190713s2018 ua ho f m 000 0 eng d EG-GiCUC eng EG-GiCUC eng Deposite Ph.D Cai01.11.28.Ph.D.2018.Su.A Susan Mohamed Amer Autoantibody pattern in Egyptian juvenile dermatomyositis patients / Susan Mohamed Amer ; Supervised Samia Salah Eldin Mahmoud , Azza Abdelkadr Elhamshary , Samar Mohamed Sabri نمط الأضداد الذاتية في مرضى التهاب الجلد والعضلات المصريين Cairo : Susan Mohamed Amer , 2018 200 P. : facsimiles , ohptpghraphs ; 25cm Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics Juvenile dermatomyositis (JDM), the most common inflammatory myopathy of child hood, is a rare multisystemic autoimmune vasculopathy. This study assesses autoantibody pattern in Egyptian patients with Juvenile dermatomyositis. This study conducted on 11 JDM patients. Serum autoantibody level was measured using extractable nuclear antigens by hybridization. The age of patients ranged from 5.5 to 15 years with a mean of 10.3 years. Sixty four% (64%) of JDM patients were females and thirty six% (36%) were males with a male to female ratio 1:2. The most common presenting manifestations in the study group were musculoskeletal manifestations (100%) dermatological manifestations (100%), and difficulty of swallowing (dysphagia) (9%). EMG was done for all patient and there was myopathic changes in (100%) of patients. Our results for autoantibodies done in this study were negative.Conclusion: Serum autoantibodies done in the study cannot be used as reliable marker for diagnosis or assessing disease activity Issued also as CD Autoantibody Juvenile dermatomyositis Myopathy and vasculopathy Azza Abdelkadr Elhamshary , Supervisor Samia Salah Eldin Mahmoud , Supervisor http://172.23.153.220/th.pdf Nazla Revisor Shimaa Cataloger ddc TH 72801 72801 ddc 0 CUCL cl210 2024-02-11 Cai01.11.28.Ph.D.2018.Su.A 01010110078676000 2023-09-22 00:00:00 TH ddc 0 CUCL cl2u8 2024-02-11 Cai01.11.28.Ph.D.2018.Su.A 01020110078676000 2023-09-22 00:00:00 78676.CD CD