Gihan Essam Eldin Elhennawy <br/><br/>
Different FDG PET/CT parameters in assessment of therapy response in pediatric patients with Ewing family of tumors /  
 مختلف معايير الفحص البوزيتروني المقطعي في تقييم علاج مرضي أطفال عائلة أورام أوينج  
Gihan Essam Eldin Elhennawy ; Supervised Hosna Mohamed Moustafa , Walid Soliman Omar , Naglaa Abdelreheem Elkinaai  
 - Cairo :   Gihan Essam Eldin Elhennawy ,   2019 
 - 144 P. :   facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Nuclear Medicine  
<br/><br/> This is a prospective study of 58 patients with pathologically proved  Ewing sarcoma . Multiple PET imaging parameters have been used to predict histologic response. Our study showed 90% reduction in TLG is predictor of histological response while other PET parameters do not predict histological response including SUVmax . Also , it showed that 60 ml pre-local control TLG value is an appropriate cut off for prediction of histological response . Results : PET/CT is superior to conventional metastatic work-up in initial staging with higher sensitivity . 90% reduction of TLG at the threshold of hepatic reference SUVmean can predict poor histological response . Cut off SUVmax2.5 can predict histological response  with wide confidence interval  
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<br/><br/><label>Subjects--Index Terms: </label>Ewing Sarcoma   PET/CT    SUVmax